HISTOLAB AZULENE DNA CREAM
Ingredients and claims, checked

Last checked September 14, 2026
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What is it like at a glance?
What the ingredients do
Hydration and softening lead, with 8 of 81 ingredients each. It also contains Niacinamide.
By skin type
- DryGood fit
- OilyNot a fit
- CombinationUse with care
- SensitiveGood fit
Piboo’s rating from user reports.
What is this product?
- What to expect
- This cream is registered in Korea as a functional cosmetic for brightening and wrinkle improvement.
- Key ingredients
- Niacinamide, Adenosine, Sodium DNA 0.1%
- When
- Morning and evening
It comes in 80 ml and 500 ml sizes, and Guaiazulene is a soothing ingredient.
Who is it for?
Less suited to
- People avoiding essential oils
What's good, and what to watch for?
Good points
- Contains Sodium DNA 0.1%
- Registered as a brightening and wrinkle-care functional cosmetic
- Guaiazulene calms the skin
Watch-outs
- Contains essential oil (Melaleuca Alternifolia (Tea Tree) Leaf Oil)
- Contains drying alcohol
- If you clog easily: Butyrospermum Parkii (Shea) Butter, Beeswax
- If you get fungal acne: Hydrogenated Vegetable Oil, Polysorbate 80
How do you use it?
- Where in your routine
- Final leave on step, after serum or ampoule
- Pairs well with
- A soothing ampoule or serum applied underneath
- A separate sunscreen in the morning
- Don't combine with
- Other leave on products carrying tea tree oil or propolis
What is in it?
The full ingredient list as the brand publishes it, in the printed order. Tap a name to read about that ingredient.
This brand publishes its ingredient list in Korean only. Names below are the matching INCI names from the Korean Cosmetic Association ingredient dictionary, except 1 with no dictionary entry, left in Korean.
Key ingredientWorth a closer look
- Water
- Butylene Glycol
- Cetyl Ethylhexanoate
- Glycerin
- Cetearyl Alcohol
- Butyrospermum Parkii (Shea) Butter
- Niacinamide
- Beeswax
- Diisostearyl Malate
- Hydrogenated Vegetable Oil
- Polysorbate 80
- Sodium DNA
- Guaiazulene
- Adenosine
- Acetyl Hexapeptide-8
- Copper Tripeptide-1
- Madecassoside
- Palmitoyl Pentapeptide-4
- Palmitoyl Tripeptide-1
- Tripeptide-1
- Hexapeptide-9
- Nicotinoyl Hexapeptide-44
- Nonapeptide-1
- sh-Oligopeptide-1
- sh-Polypeptide-1
- sh-Polypeptide-16
- 에스에이치-폴리펩타이드-4
- Allantoin
- Glyceryl Stearate
- Panthenol
- Tocopheryl Acetate
- Melaleuca Alternifolia (Tea Tree) Leaf Oil
- Propolis Extract
- Sodium Hyaluronate
- Centella Asiatica Extract
- Ceramide NP
- Glycine
- Hamamelis Virginiana (Witch Hazel) Extract
- Polygonum Cuspidatum Root Extract
- Portulaca Oleracea Extract
- Scutellaria Baicalensis Root Extract
- Serine
- Glutamic Acid
- Camellia Sinensis Leaf Extract
- Glycyrrhiza Glabra (Licorice) Root Extract
- Aspartic Acid
- Leucine
- Ethylhexylglycerin
- Chamomilla Recutita (Matricaria) Flower Extract
- Rosmarinus Officinalis (Rosemary) Leaf Extract
- Alanine
- Lysine
- Tyrosine
- Phenylalanine
- Proline
- Threonine
- Valine
- Polysorbate 20
- Isoleucine
- Caprylyl Glycol
- Disodium Phosphate
- Histidine
- Cysteine
- Methionine
- Lecithin
- Sodium Phosphate
- Alcohol
- Sorbitan Oleate
- Disodium EDTA
- Hydroxyethylcellulose
- 1,2-Hexanediol
- Polysorbate 60
- Sorbitan Sesquioleate
- Ethyl Hexanediol
- Vinyl Dimethicone
- Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
- Isohexadecane
- Arginine
- Carbomer
- Glyceryl Caprylate
- Ascorbyl Tetraisopalmitate
Ingredients with no mark are ones we found nothing notable about, and when marks overlap on one ingredient we show the caution first.
What the claims add up to
- You can expect:
- less visible dark spots · softer-looking fine lines
- Only partly backed:
- better hydration · calmer skin (amount unknown)
- Don't count on:
- firmer skin · better barrier support · a brighter skin tone
See each claim, checked (33)
Claims, checked
Use until the period stated on the product
backed by evidenceResponsible cosmetics seller: Medians Co., Ltd. / Cosmetics manufacturer: Medians Lab Co., Ltd.
backed by evidenceDual functional cosmetic for whitening and wrinkle improvement
backed by evidenceHelps with skin whitening. Helps with skin wrinkle improvement.
backed by evidenceThis product may be exchanged or compensated in accordance with the Consumer Dispute Resolution Standards announced by the Fair Trade Commission.
backed by evidence1. If abnormal symptoms or side effects such as red spots, swelling, or itching occur on the application site due to direct sunlight during or after use, consult a specialist, etc. 2. Refrain from use on areas with wounds, etc. 3. Precautions for storage and handling: a) Keep out of reach of children b) Store away from direct sunlight
backed by evidenceDual functional: wrinkle improvement and whitening
backed by evidenceAmino Acid Complex 17 types of amino acids / A substance composed of a total of 17 amino acids, it evenly delivers essential nutrients to each layer of the skin. It supplies nutrients to the skin and helps with skin condition care as a raw material for collagen, elastin, and hyaluronic acid. *The above description is limited to raw material properties
backed by evidence*The above clinical data are the results of a test conducted by Medians' affiliated research institute.
backed by evidenceHow to use! / At the final step of skincare, take an appropriate amount, spread it gently over the entire face, and pat to absorb.
backed by evidenceHistolab is not sold online.
backed by evidenceMoisture barrier formation / Forms a moisture barrier on the skin leaving no room for dryness.
plausible, not tested[For Consumer] 80ml / [For Bulk] 500ml
partly backedAZULENE DERMA SCIENCE Real calming solution with azulene energy for sensitive skin / HIGH TECH SKIN CARE Cream helps soothe and revitalize the skin with Sodium DNA / 80 ml / 2.7 fl.oz
partly backedSimultaneous soothing and nutrition care / A solution cream where Azulene and DNA meet.
partly backedContains Azulene, a powerful soothing ingredient extracted from chamomile flowers, and DNA, a key ingredient, to help care for sensitive and loose skin.
partly backedGuaiazulene / An ingredient extracted in high purity by distilling chamomile, it helps soothe and protect skin that easily becomes sensitive and heated by external environments. It is characterized by its own natural blue color from the ingredient, not artificially colored.
partly backedMULTIEX BSASM® PLUS Skin soothing / Quickly soothes sensitive skin with 7 natural compound plant extracts / Patent registration number: 10-0490212
partly backedHuman application test / Skin application test results of Histolab Azulene DNA Cream!
partly backedWrinkles / Wrinkle Percent = 40.2% (Before use) / Wrinkle Percent = 37.9% (After 10 days) / The more the gray area decreases, the better the skin smoothness.
partly backedSkin remodeling effect of two patented ingredients.
overstatedSodium DNA (PDRN), a key ingredient for skin elasticity, is DNA extracted from salmon testes, rich in omega-3 and essential vitamins, and is widely used for food intake as well as for its high human compatibility. *The above description is limited to raw material properties
overstatedElasticity / Pores Count = 2,927 (Before use) / Pores Count = 2,682 (After 10 days) / A decrease in the number indicates improved elasticity.
overstatedPrimary soothing care cream that delivers nutrients to the skin.
no supporting source foundA cream layering two patented ingredients step by step / Two patented ingredients, including Medians' exclusive patented ingredient SRGF H1 Complex™, soothe the skin and build up nutrients layer by layer to strengthen it.
no supporting source foundSRGF H1 COMPLEX™ Skin barrier strengthening / An exclusive patented peptide strengthens the skin barrier to create healthy, vibrant skin / Patent registration number: 10-10579310
no supporting source foundA *LTE low-temperature manufacturing method to fully contain active ingredients / *LTE: Low Temperature Emulsification / Histolab Azulene DNA Cream was made slowly over a long time at low temperature to fully contain active ingredients. / Low-temperature method step 1: Undergoes a cooling process to prevent moisture evaporation / Low-temperature method step 2: Active ingredients are added to the low-temperature base / Low-temperature method step 3: Slow mixing to prevent molecules from breaking
no supporting source found2021.10.18 - 10.27 / This is the test result from Medians' affiliated research institute's internal test. The increase in the blue range and the decrease in the yellow and red ranges indicate that reddish areas disappear and skin tone becomes brighter and more even.
no supporting source foundAZULENE DERMA SCIENCE helps soothe the sensitive skin with botanical ingredients / HICH TECH SKINCARE helps soothe the sensitive skin with botanical ingredients / 80 ml / 6.8 fl.oz
contradicted by sourcesIt is more effective to deliver nutrients after preparing the skin to absorb active ingredients well.
nothing specific to checkThe culmination of Histolab's beauty philosophy that soothes and protects tired skin.
nothing specific to checkPlenty of skin soothing and nutrition! Azulene X DNA
nothing specific to checkEven better when used together: Histolab Azulene skincare / Nurtures healthy skin with step-by-step soothing care.
nothing specific to check
We quote each claim exactly as the brand published it, then check it against the ingredient list and the brand's own documents.