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HISTOLAB AZULENE DNA CREAM

Ingredients and claims, checked

Product photo of HISTOLAB AZULENE DNA CREAM

Last checked September 14, 2026

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What is it like at a glance?

What the ingredients do

Hydration and softening lead, with 8 of 81 ingredients each. It also contains Niacinamide.

Hydration
8
Softening
8
Brightening
2
Wrinkle improvement
1

By skin type

  • DryGood fit
  • OilyNot a fit
  • CombinationUse with care
  • SensitiveGood fit

Piboo’s rating from user reports.

Worth knowing

  • Contains essential oil
  • Contains drying alcohol
  • Has a fungal-acne trigger
  • On pore-clogging lists

What is this product?

What to expect
This cream is registered in Korea as a functional cosmetic for brightening and wrinkle improvement.
Key ingredients
Niacinamide, Adenosine, Sodium DNA 0.1%
When
Morning and evening

It comes in 80 ml and 500 ml sizes, and Guaiazulene is a soothing ingredient.

Who is it for?

Less suited to

  • People avoiding essential oils

What's good, and what to watch for?

Good points

  • Contains Sodium DNA 0.1%
  • Registered as a brightening and wrinkle-care functional cosmetic
  • Guaiazulene calms the skin

Watch-outs

  • Contains essential oil (Melaleuca Alternifolia (Tea Tree) Leaf Oil)
  • Contains drying alcohol
  • If you clog easily: Butyrospermum Parkii (Shea) Butter, Beeswax
  • If you get fungal acne: Hydrogenated Vegetable Oil, Polysorbate 80

How do you use it?

Where in your routine
Final leave on step, after serum or ampoule
Pairs well with
  • A soothing ampoule or serum applied underneath
  • A separate sunscreen in the morning
Don't combine with
Other leave on products carrying tea tree oil or propolis

What is in it?

The full ingredient list as the brand publishes it, in the printed order. Tap a name to read about that ingredient.

This brand publishes its ingredient list in Korean only. Names below are the matching INCI names from the Korean Cosmetic Association ingredient dictionary, except 1 with no dictionary entry, left in Korean.

Key ingredientWorth a closer look

Ingredients with no mark are ones we found nothing notable about, and when marks overlap on one ingredient we show the caution first.

What the claims add up to

You can expect:
less visible dark spots · softer-looking fine lines
Only partly backed:
better hydration · calmer skin (amount unknown)
Don't count on:
firmer skin · better barrier support · a brighter skin tone
See each claim, checked (33)

Claims, checked

  • Use until the period stated on the productbacked by evidence
  • Responsible cosmetics seller: Medians Co., Ltd. / Cosmetics manufacturer: Medians Lab Co., Ltd.backed by evidence
  • Dual functional cosmetic for whitening and wrinkle improvementbacked by evidence
  • Helps with skin whitening. Helps with skin wrinkle improvement.backed by evidence
  • This product may be exchanged or compensated in accordance with the Consumer Dispute Resolution Standards announced by the Fair Trade Commission.backed by evidence
  • 1. If abnormal symptoms or side effects such as red spots, swelling, or itching occur on the application site due to direct sunlight during or after use, consult a specialist, etc. 2. Refrain from use on areas with wounds, etc. 3. Precautions for storage and handling: a) Keep out of reach of children b) Store away from direct sunlightbacked by evidence
  • Dual functional: wrinkle improvement and whiteningbacked by evidence
  • Amino Acid Complex 17 types of amino acids / A substance composed of a total of 17 amino acids, it evenly delivers essential nutrients to each layer of the skin. It supplies nutrients to the skin and helps with skin condition care as a raw material for collagen, elastin, and hyaluronic acid. *The above description is limited to raw material propertiesbacked by evidence
  • *The above clinical data are the results of a test conducted by Medians' affiliated research institute.backed by evidence
  • How to use! / At the final step of skincare, take an appropriate amount, spread it gently over the entire face, and pat to absorb.backed by evidence
  • Histolab is not sold online.backed by evidence
  • Moisture barrier formation / Forms a moisture barrier on the skin leaving no room for dryness.plausible, not tested
  • [For Consumer] 80ml / [For Bulk] 500mlpartly backed
  • AZULENE DERMA SCIENCE Real calming solution with azulene energy for sensitive skin / HIGH TECH SKIN CARE Cream helps soothe and revitalize the skin with Sodium DNA / 80 ml / 2.7 fl.ozpartly backed
  • Simultaneous soothing and nutrition care / A solution cream where Azulene and DNA meet.partly backed
  • Contains Azulene, a powerful soothing ingredient extracted from chamomile flowers, and DNA, a key ingredient, to help care for sensitive and loose skin.partly backed
  • Guaiazulene / An ingredient extracted in high purity by distilling chamomile, it helps soothe and protect skin that easily becomes sensitive and heated by external environments. It is characterized by its own natural blue color from the ingredient, not artificially colored.partly backed
  • MULTIEX BSASM® PLUS Skin soothing / Quickly soothes sensitive skin with 7 natural compound plant extracts / Patent registration number: 10-0490212partly backed
  • Human application test / Skin application test results of Histolab Azulene DNA Cream!partly backed
  • Wrinkles / Wrinkle Percent = 40.2% (Before use) / Wrinkle Percent = 37.9% (After 10 days) / The more the gray area decreases, the better the skin smoothness.partly backed
  • Skin remodeling effect of two patented ingredients.overstated
  • Sodium DNA (PDRN), a key ingredient for skin elasticity, is DNA extracted from salmon testes, rich in omega-3 and essential vitamins, and is widely used for food intake as well as for its high human compatibility. *The above description is limited to raw material propertiesoverstated
  • Elasticity / Pores Count = 2,927 (Before use) / Pores Count = 2,682 (After 10 days) / A decrease in the number indicates improved elasticity.overstated
  • Primary soothing care cream that delivers nutrients to the skin.no supporting source found
  • A cream layering two patented ingredients step by step / Two patented ingredients, including Medians' exclusive patented ingredient SRGF H1 Complex™, soothe the skin and build up nutrients layer by layer to strengthen it.no supporting source found
  • SRGF H1 COMPLEX™ Skin barrier strengthening / An exclusive patented peptide strengthens the skin barrier to create healthy, vibrant skin / Patent registration number: 10-10579310no supporting source found
  • A *LTE low-temperature manufacturing method to fully contain active ingredients / *LTE: Low Temperature Emulsification / Histolab Azulene DNA Cream was made slowly over a long time at low temperature to fully contain active ingredients. / Low-temperature method step 1: Undergoes a cooling process to prevent moisture evaporation / Low-temperature method step 2: Active ingredients are added to the low-temperature base / Low-temperature method step 3: Slow mixing to prevent molecules from breakingno supporting source found
  • 2021.10.18 - 10.27 / This is the test result from Medians' affiliated research institute's internal test. The increase in the blue range and the decrease in the yellow and red ranges indicate that reddish areas disappear and skin tone becomes brighter and more even.no supporting source found
  • AZULENE DERMA SCIENCE helps soothe the sensitive skin with botanical ingredients / HICH TECH SKINCARE helps soothe the sensitive skin with botanical ingredients / 80 ml / 6.8 fl.ozcontradicted by sources
  • It is more effective to deliver nutrients after preparing the skin to absorb active ingredients well.nothing specific to check
  • The culmination of Histolab's beauty philosophy that soothes and protects tired skin.nothing specific to check
  • Plenty of skin soothing and nutrition! Azulene X DNAnothing specific to check
  • Even better when used together: Histolab Azulene skincare / Nurtures healthy skin with step-by-step soothing care.nothing specific to check

We quote each claim exactly as the brand published it, then check it against the ingredient list and the brand's own documents.

How we check claims