What is Palmitoyl Pentapeptide-4?
Skin conditioning, miscellaneous
Palmitoyl Pentapeptide-4 is a skin conditioner that helps soften and smooth the surface.
This ingredient is listed in CosIng, the EU's cosmetic ingredient database. CosIng lists what it's used for as: Skin conditioning, miscellaneous.
CosIng function classes are the EU's standard list of the jobs an ingredient does inside a product, such as moisturizing, emulsifying, or preserving.
Which products feature it?
30 of the 2320 products we've checked feature this as a key ingredient. Products that disclose a concentration or list it near the top of the ingredient list come first.
Showing 1 to 12.

AXIS-Y
Vegan Collagen Eye Serum
It's made for better hydration and calmer skin.
Key: Palmitoyl Pentapeptide-4 (#12 on the ingredient list), Niacinamide, Adenosine
26 claims, summarized
- Only partly backed:
- better hydration (amount unknown) · firmer skin (amount unknown) · calmer skin
- Don't count on:
- a brighter skin tone
See each claim
claims, checked
Jojoba seed oil moisturizing and soothing
plausible, not testedSunflower seed oil moisturizing and nourishment
plausible, not testedTriple hyaluronic acid skin moisture supply and retention
plausible, not testedBased on a single use, the amount is easy to control, and you can massage around the eyes coolly without irritation.
plausible, not testedIt cares for fine lines around sensitive and dry eyes from fine lines to deep wrinkles, provides a moist moisturizing feeling, and helps relieve eye puffiness and dark circles.
partly backedThrough the combination of vegan collagen and a 5-peptide complex, it helps improve skin elasticity, and triple hyaluronic acid helps with moisture care around the eyes, providing synergistic care for moist eyes.
partly backed3 minutes after a single use, eye puffiness reduction by 14%
partly backedAfter 2 weeks of use, dark circle relief by 7%
partly backedDetermined non-irritating in tests at a specialized human application testing institution
partly backedDetermined non-irritating for sensitive skin at a specialized human application testing institution
partly backedElasticity + conditioning effects delivered by 5 peptides
partly backedAfter one use, the puffiness reduction effect felt within 3 minutes
partly backedAfter 2 weeks of use, improvement in 4 types of eye wrinkles by 67%
overstatedAfter 2 weeks of use, improvement of under-eye sagging (eye bags) by 22%
overstatedSix plant-derived ingredients
overstatedGently massaging any area where wrinkles are a concern helps improve wrinkles.
overstatedHwahae 2026 first half efficacy/effect awards eye care category 1st place
no supporting source foundGreen apple moisture supply and tone care
no supporting source foundGreen grape (Shine Muscat) moisturizing and vitality care
no supporting source foundGreen plum skin moisturizing and soothing
no supporting source foundA high-purity low-molecular-weight collagen ingredient very similar to human collagen, which helps improve wrinkles and elasticity.
no supporting source foundHigh-moisturizing ingredients sunflower seed and jojoba seed are microsomed (=split) into 1/250th the size of a pore, providing moisture and hydrating sensation to dry eye area skin, helping effective wrinkle care.
no supporting source foundCustomer satisfaction with eye area improvement after 2 weeks of product use
no supporting source foundCosmetic certified by the Korea Vegan Certification Institute
no supporting source foundCosmetic that does not involve animal testing
no supporting source foundVegan collagen eye serum offering an unmissable 360-degree° eye care solution
nothing specific to check
Centellian24
Centellian24 Wrinklecell Core Eye Cream
Key: Palmitoyl Pentapeptide-4 (#14 on the ingredient list), Copper Tripeptide-1, Palmitoyl Tripeptide-1
It's registered in Korea as a functional cosmetic for wrinkle improvement.
Key: Palmitoyl Pentapeptide-4 (#17 on the ingredient list), Adenosine, Tripeptide-1
6 claims, summarized
- You can expect:
- softer-looking fine lines
See each claim
claims, checked
Wrinkle-improving functional cosmetic
backed by evidenceToner that smoothly adheres to dense pore texture
partly backedProprietary patent Botul-Peptide™
overstatedInner pore elasticity
no supporting source foundPore scaling
no supporting source foundPore prescription
nothing specific to check
MARSHIQUE
Wrinkle Repair Smile Line Patch
Key: Palmitoyl Pentapeptide-4 (#20 on the ingredient list), Adenosine, Hydrolyzed Collagen
4 claims checked
claims, checked
Clinically proven wrinkle improvement
plausible, not testedPrevents wrinkles with tight fixation
no supporting source foundMarssik wrinkle patch 8.48% vs our essence 3.08% (275% UP)
no supporting source foundOlive Young online mall overall sales ranking No. 1 (as of 2024.12.30)
no supporting source found

S.NATURE
Super Aquagel Oasis Ampule Mask
It's made for calmer skin and better hydration.
Key: Palmitoyl Pentapeptide-4 (#21 on the ingredient list), Hyaluronic Acid, Hydrolyzed Collagen
7 claims, summarized
- Only partly backed:
- better hydration · calmer skin (amount unknown)
- Don't count on:
- a brighter skin tone · firmer skin
See each claim
claims, checked
Enriched with Allantoin, Paeonia Suffruticosa Root Extract and Betaine to soothe irritated and sensitive skin from daily irritation and external aggressors.
plausible, not testedWith a full moisture sensation, it cares for the skin to be moist and elastic.
plausible, not testedFormulated with 8 types of Hyaluronic Acids to boost skin moisture and create plump and radiant skin.
partly backedPacked with Collagen, 5 types of Peptide and Arginine to enhance skin elasticity and brighten up skin tone for achieving a clear and smooth complexion.
overstatedFeatures a vegan-certified aqua-gel sheet with minimal irritation to skin.
no supporting source foundThis intensive moisturizing sheet mask recharges dry and tired skin with rich moisture and nourishment.
nothing specific to checkMoisture that fills with elasticity
nothing specific to check
With Betaine, you can expect better hydration.
Key: Palmitoyl Pentapeptide-4 (#25 on the ingredient list), Niacinamide 10%, Adenosine
15 claims, summarized
- You can expect:
- better hydration · better barrier support
- Only partly backed:
- softer-looking fine lines (amount unknown) · firmer skin (amount unknown)
- Free of:
- the ingredients it lists
See each claim
claims, checked
High-content Niacinamide Antioxidant Lotion
backed by evidenceResveratrol (Antioxidant), Allantoin, Betaine (Barrier, Moisture)
backed by evidenceDaily moisturizing that lightly fills moisture and barrier
backed by evidenceNo artificial fragrance added
backed by evidenceA step that strengthens the skin barrier and protective film against broken skin barrier and chronic inner dryness, fills the skin with moisture, and adds a comfortable moisturizing feel for more elastic and smooth skin.
plausible, not testedWrinkle improvement
partly backedMoisturizing care for strengthening the skin barrier and firm skin elasticity
partly backedNiacinamide (Brightening, Antioxidant, Elasticity, Oil-Moisture Balance)
partly backedEGF, Peptide (Elasticity), Adenosine (Wrinkle Improvement Functional)
partly backedSkin barrier, elasticity, moisture, wrinkle improvement
partly backedBalance of high active ingredient content and comfortable feel
partly backedAll Maitton products contain 10% Niacinamide, an antioxidant ingredient verified through in-house research.
partly backedLow-irritation test completed
no supporting source foundAfter using toner to refine the skin or allowing the ampoule to absorb, take 1~2 pumps onto your hand or face and spread evenly to absorb. After it is fully absorbed, applying about 1 pump more will give you even better results.
nothing specific to checkHigh-content Niacinamide skincare created by aging research experts, effective and reasonable antioxidant basic cosmetics
nothing specific to check

Biodance
Collagen Cleansing Oil
Key: Palmitoyl Pentapeptide-4 (#25 on the ingredient list), Collagen Extract, Acetyl Hexapeptide-8
1 claim checked
claims, checked
Skincare starting with cleansing
nothing specific to check

Theralogic
Retinal Wrinkle-Elasticity Cream
Key: Palmitoyl Pentapeptide-4 (#26 on the ingredient list), Retinal, Niacinamide

REJURAN
Healer Triple Radiance Cream
Key: Palmitoyl Pentapeptide-4 (#28 on the ingredient list), Niacinamide, Saccharomyces Extract
2 claims checked
claims, checked
Melanin Clear
partly backed3STEP
nothing specific to check
Key: Palmitoyl Pentapeptide-4 (#29 on the ingredient list), Niacinamide, Adenosine
1 claim checked
claims, checked
Intensive wrinkle, elasticity, and lifting care
no supporting source found
Key: Palmitoyl Pentapeptide-4 (#30 on the ingredient list), Palmitoyl Tripeptide-1, Hexapeptide-9
Key: Palmitoyl Pentapeptide-4 (#31 on the ingredient list), Adenosine, Capryloyl Salicylic Acid
7 claims, summarized
- Don't count on:
- less visible pores · firmer skin
See each claim
claims, checked
For functional cosmetics under the Cosmetics Act (whitening, wrinkle improvement, UV protection products, etc.): Not applicable
backed by evidence3-second pore elasticity! 4-section customized pad for concern areas
partly backedWith the 4-section pad, you can intensively manage skin concern areas.
partly backedContains Dewytree's proprietary ingredient Chocollagen™.
partly backedThe triple pore booster containing Phyto PDRN improves eye area‧nasolabial fold wrinkles.
overstatedIt manages sagging horizontal and vertical pores with elasticity.
no supporting source foundHuman application tests were conducted to prove the wrinkle care effect.
no supporting source found
Often featured alongside it
Are the claims about it backed up?
We checked each claim that features this ingredient. Open the list below to see the result for each one.
See the results by claim
| Result | Claims |
|---|---|
| backed by evidence | 1 of 14 |
| plausible, not tested | 1 of 14 |
| partly backed | 6 of 14 |
| overstated | 3 of 14 |
| no supporting source found | 1 of 14 |
| nothing specific to check | 2 of 14 |
These are counts of claims, not products. One product can name the same ingredient in several claims, and we checked each one on its own.


