What is Lactobacillus Ferment Lysate?
Skin conditioning
Lactobacillus Ferment Lysate is a skin conditioner that helps soften and smooth the surface.
This ingredient is listed in CosIng, the EU's cosmetic ingredient database. CosIng lists what it's used for as: Skin conditioning.
CosIng function classes are the EU's standard list of the jobs an ingredient does inside a product, such as moisturizing, emulsifying, or preserving.
Anything to watch out for?
Some products' ingredient lists mark this ingredient as below. If a mark's reason fits your skin, it is the ingredient to weigh in those products.
- This is a fungal-acne trigger, one of the ingredients people with fungal acne avoid.
- Marked this way on 98 products.
Each mark comes from matching the product's full ingredient list against lists for fragrance, labeled fragrance allergens, drying alcohols, essential oils, fungal acne, pore clogging, and pregnancy caution.
Which products feature it?
27 of the 2320 products we've checked feature this as a key ingredient. Products that disclose a concentration or list it near the top of the ingredient list come first.
Showing 1 to 12.
Laboreve
PeachMicrobiome 78 PDRN Toner
It's made for better hydration and calmer skin.
Key: Lactobacillus Ferment Lysate (#1 on the ingredient list · 78%), Hydrolyzed Ovum DNA, Niacinamide
10 claims, summarized
- Only partly backed:
- better hydration · calmer skin · better barrier support
- Don't count on:
- a brighter skin tone
See each claim
claims, checked
78% PEACH FERMENT] Formulated with 78% peach ferment instead of water, this toner delivers lightweight hydration and promotes smoother, vibrant-looking skin. The nutrient-rich peach ferment leaves skin soft, supple, and refreshed.
partly backedMILKY TONER TEXTURE] A soft milky toner texture glides onto the skin and absorbs quickly without a sticky finish, leaving skin comfortably hydrated and ready for the next step.
partly backedIs this toner suitable for sensitive and dry skin? Formulated with Panthenol to calm and strengthen reactive skin, while the 78% fermented lactobacillus base supports the skin barrier. As always, we recommend a patch test before first use, especially for highly sensitive skin types.
partly backedVEGAN PDRN] Infused with vegan PDRN, this formula works to support the skin barrier and maintain overall balance, leaving the complexion feeling resilient and comfortable.
overstatedFOR SENSITIVE SKIN] Created for delicate skin, this toner helps calm the look of stressed skin and provides gentle daily care for a balanced, refreshed skin appearance.
overstatedIt blends PDRN into peach-derived lactobacillus ferment lysate to help with skin soothing, recovery of damaged cells and promotion of skin regeneration
overstated'Peach Microbiome 78 PDRN Toner' is a product that adds PDRN to peach-derived lactobacillus ferment lysate to raise the skin soothing and damaged cell recovery effects
overstatedDoes this toner contain artificial coloring or fragrances? No. The soft peach tone of the toner comes entirely from its natural formulation, not from artificial dyes or fragrances. Every ingredient is chosen to be gentle and skin-friendly.
no supporting source foundWhy should I use this toner? Laboreve Peach Toner uses 78% Lactobacillus Ferment Lysate as its base, concentrated probiotic essence, not diluted hydration. With consistent use, expect a visibly stronger, more resilient skin barrier over time.
no supporting source foundKOREAN SKIN CARE] Inspired by modern Korean skin care routines, this peach-powered toner highlights nourishment and glow for a radiant, balanced-looking finish.
nothing specific to check
It's registered in Korea as a functional cosmetic for brightening and wrinkle improvement.
Key: Lactobacillus Ferment Lysate (#1 on the ingredient list · 56.88%), Retinol, Hydroxypinacolone Retinoate
25 claims, summarized
- You can expect:
- less visible dark spots · softer-looking fine lines
- Only partly backed:
- firmer skin (amount unknown) · better hydration · less visible pores (amount unknown) · better barrier support (amount unknown)
- Don't count on:
- calmer skin
See each claim
claims, checked
Dual functional for wrinkles & whitening.
backed by evidenceCares for butterfly zone pores, dull complexion, sagging skin lacking elasticity, and uneven texture.
plausible, not testedSqualane: Provides moisture and nutrition simultaneously to complete a firm skin finish.
plausible, not testedPrimary skin irritation test completed.
plausible, not testedDermatological test completed (skin irritation response SCORE 0.00).
plausible, not testedNon-comedogenic test completed on sensitive skin.
plausible, not testedA high-efficiency ampoule that simultaneously manages pore texture and inner glow through the synergy of potent Green Tea PDRN™ and Retinol.
partly backedAs a low-irritation formula with a sensitive skin irritation response of 0.00, it is a dual-functional cosmetic for wrinkle improvement and whitening that smooths rough skin texture and bestows an elastic glow.
partly backedConfirmed 2.33 times more powerful repair effect of Green Tea PDRN™ compared to commercial salmon PDRN reagent*(*Results of in-vitro test comparing the repair efficacy of Green Tea PDRN™ and salmon PDRN reagent)
partly backedVegan PDRN sourced from clean Jeju green tea fields, not extracted from animal-derived ingredients.
partly backedGreen Tea PDRN™ (lactobacillus ferment lysate derived from lactic acid bacteria obtained from Jeju green tea): Repair / Helps skin repair as vegan PDRN derived from skin-beneficial lactic acid bacteria from green tea.
partly backedTriple Retinol Complex™ (Pure Retinol 1,000 IU/g + Dual Retinoid 1,150 ppm): Elasticity, antioxidant, moisture / Helps promote skin turnover and smooth skin texture, densely fills elasticity in stretched and enlarged pore areas.
partly backedThrough the synergy of Retinol and PDRN, it densely cares for the number, area, depth, and volume of pores to complete a firm skin foundation. In particular, the effect of improving pore concerns was confirmed after 4 weeks, and you can expect the effect of filling the skin with elasticity from within when used.
partly backedGreen Tea PDRN™ contained in the Retinol PDRN Skin Booster Ampoule was confirmed to have a 2.33 times more powerful repair effect than commercial salmon PDRN reagent, as measured in the control group after 16 hours. This ingredient is a vegan PDRN extracted through microbial culture technology derived from Jeju green tea, and it plays a role in building a strong skin barrier.
partly backedThe Retinol PDRN Skin Booster Ampoule has been certified as a dual-functional cosmetic for wrinkle improvement and whitening as notified by the Ministry of Food and Drug Safety. The retinol ingredient promotes the skin turnover cycle to create a smooth skin texture, and densely fills elasticity in the butterfly zone and nasolabial folds, helping to manage skin that shines both inside and out.
partly backedAfter 4 weeks of use, proved a 26.4% improvement in inner glow and a 39.8% reduction in pore area,
partly backedPore texture & inner glow, improves both outer and inner elasticity of pores to create smooth pore texture and skin that shines both inside and out!
overstatedA low-irritation daily retinol ampoule that recorded a sensitive skin irritation response of 0.00 and can be used daily without irritation.
overstatedYarrow Extract: Excellent for soothing the skin and anti-inflammatory effects, suitable for sensitive skin. Also rich in antioxidants, helps prevent aging.
overstatedThe Retinol PDRN Skin Booster Ampoule is a product that received a low-irritation rating with a sensitive skin irritation response of 0.00. Having completed primary skin irritation testing and non-comedogenic testing, it is a low-irritation, high-efficiency formula that can be used daily without burden even on sensitive skin.
overstatedWith 3.4 times stronger absorption, it densely fills elasticity from deep within the skin,
no supporting source foundWith a size 1/20,000th of a pore, it delivers absorption of a different dimension, densely reaching deep into the skin.
no supporting source foundGreen Tea Ceramide: Soothes skin and cares for the moisture barrier.
no supporting source foundPDRN: Technology: Liposome method / Strengthens the skin barrier and improves skin condition.
no supporting source foundA next-generation skin booster born from the meeting of Retinol and PDRN.
nothing specific to check
It's made for firmer skin and better barrier support.
Key: Lactobacillus Ferment Lysate (#2 on the ingredient list · 15.5%), Niacinamide, Adenosine
4 claims, summarized
- You can expect:
- firmer skin
- Only partly backed:
- better barrier support (amount unknown)
See each claim
claims, checked
Rejuderm Cream contains 15.5% of the microorganism-derived ingredient 'Lactobacillus Ferment Lysate,' which helps improve skin elasticity.
backed by evidenceFor sensitive skin that ages faster, a slow-aging cream that improves skin elasticity with density in just 7 days.
partly backedThe Derma Tightening Barrier Capsule contains ceramides, cholesterol, and fatty acids that make up the skin barrier, collagen that helps improve skin elasticity, and vitamin C derivative, an antioxidant ingredient that cannot be omitted in anti-aging, all contained in one capsule.
partly backedRejuderm365 Density Elasticity Capsule Cream is an elasticity cream that has completed various skin safety tests, so it can be used without worry even on sensitive skin.
no supporting source found

Laboreve
PeachMicrobiome 84 EGF Serum
It's made for better hydration and calmer skin.
Key: Lactobacillus Ferment Lysate (#4 on the ingredient list · 9%), Sh-Oligopeptide-1, Niacinamide
8 claims, summarized
- Only partly backed:
- calmer skin (amount unknown) · less visible dark spots (amount unknown) · softer-looking fine lines (amount unknown) · better hydration
See each claim
claims, checked
Natural amino acids and sugars attract moisture to maintain hydration and relieve inner dryness.
plausible, not testedPolyphenols·flavonoids and other peach extracts soothe irritated skin and relieve redness, and with the addition of niacinamide and adenosine, this is a 2-fold functional product that also offers whitening·wrinkle improvement effects.
partly backedLaboreve PeachMicrobiome Serum combines EGF-identical peptide (10ppm), triple Hyaluronic Acid, and Niacinamide — all on a 9% Lactobacillus Ferment Lysate base. With consistent use, expect visibly plumper, firmer skin that holds moisture longer.
partly backedYes — the 9% probiotic ferment base strengthens and calms the skin barrier, while Collagen (500ppm) deeply nourishes and EGF (10ppm) supports natural skin renewal. Gentle enough for daily use. Patch test recommended.
partly backed84 Billion Probiotics + EGF
overstatedIn addition to Peach Biome 028, this product contains vegan PDRN derived from that strain, EGF, allantoin, panthenol, betaine, niacinamide (vitamin B3), and other ingredients, enabling comprehensive skin balance care.
no supporting source foundThis is a high-functionality nourishing serum that intensively cares for skin weakened by repeated dryness and loss of elasticity.
nothing specific to checkThe Laboreve PeachMicrobiome 84 EGF Serum is a high-concentration serum that delivers intensive nourishment and revitalization.
nothing specific to check
Key: Lactobacillus Ferment Lysate (#4 on the ingredient list · 3.6%), Bifida Ferment Lysate 3.6%, Panthenol
BIOHEAL BOH
Bioheal Boh Probioderm 3D Lifting Cream Mist
Key: Lactobacillus Ferment Lysate (#2 on the ingredient list), Panthenol, Adenosine
BIOHEAL BOH
Probioderm 3D Lifting Emulsion
Key: Lactobacillus Ferment Lysate (#2 on the ingredient list), Lactobacillus Ferment, Panthenol
Key: Lactobacillus Ferment Lysate (#5 on the ingredient list), Sea Water
3 claims checked
claims, checked
Sprayable probiotics, emergency soothing mist
plausible, not testedPsst- the moment you spray, cool & moist! Large-capacity emergency soothing mist
overstatedVolume·Convenience·Effect MAX
nothing specific to check

SKIN&LAB
BARRIERDERM RINGER AMPOULE
It's made for better hydration and better barrier support.
Key: Lactobacillus Ferment Lysate (#7 on the ingredient list), Hyaluronic Acid, Panthenol
20 claims, summarized
- Only partly backed:
- better hydration · firmer skin · better barrier support
See each claim
claims, checked
German Derma Test社 EXCELLENT grade for once more peace of mind
backed by evidenceWe have earned an EXCELLENT grade in the skin human application (irritation) test conducted by the world-renowned skin science research institute, German Derma Test.
backed by evidenceMOISTURIZING
partly backedSMOOTHING
partly backedCALMING
partly backedMoisture accumulation up to 12 layers* of the stratum corneum
partly backedSkin moisture improvement rate 542.5%
partly backedSkin moisture improvement rate 528.61%
partly backed100-hour moisture persistence accumulation
partly backedAfter 100 hours, 92.81% improvement
partly backedRough skin texture suppleness accumulation
partly backedSkin texture 6.59% improvement
partly backedEven under physical irritation, firm barrier accumulation
partly backedSkin barrier 57.27% improvement
partly backed12-layer moisture lock
no supporting source foundMoisture Energy Water Splash Ampoule
nothing specific to checkIf you are experiencing the same symptoms as above
nothing specific to checkDon't use just any ampoule
nothing specific to checkWhat your skin needs is inner moisture, not surface moisture
nothing specific to checkFill your inner moisture to the brim with the water splash ampoule that keeps your skin comfortable
nothing specific to check
Key: Lactobacillus Ferment Lysate (#7 on the ingredient list), Lactobacillus Ferment, Adenosine
Key: Lactobacillus Ferment Lysate (#11 on the ingredient list), Salicylic Acid, Melatonin
Key: Lactobacillus Ferment Lysate (#12 on the ingredient list), Collagen Extract, Hyaluronic Acid
Often featured alongside it
Are the claims about it backed up?
We checked each claim that features this ingredient. Open the list below to see the result for each one.
See the results by claim
| Result | Claims |
|---|---|
| backed by evidence | 2 of 10 |
| partly backed | 5 of 10 |
| overstated | 2 of 10 |
| no supporting source found | 1 of 10 |
These are counts of claims, not products. One product can name the same ingredient in several claims, and we checked each one on its own.




